— Expertise
Filling Lines
Deep specialization in sterile filling lines —From containers washing and depyrogenation filling, stoppering, crimping, and inspection. Decades of hands-on experience with every major filling technology and vendor in the global market.
Complete Line Configuration
End-to-end filling line expertise from container entry to finished product exit
1
Washing Machine
Container cleaning — WFI final rinse, validated cleaning cycles.
2
Depyrogenation Tunnel
Dry heat depyrogenation at ≥250°C. Continuous operation, validated FH values, temperature uniformity mapping.
3
Filling Machine
Multiple filling technologies — piston, peristaltic pump, rotary piston, time-pressure. Dosing accuracy, CIP/SIP capability.
4
Stoppering & Crimping
Stopper placement, aluminum cap crimping, seal integrity verification, sealing force verification. Critical for container closure integrity (CCI).
5
Lyophilization
Controlled freeze-drying for sensitive pharmaceutical products. Precise shelf temperature and chamber pressure control, validated cycles, CIP/SIP capability, and reliable residual moisture reduction for long-term product stability.
Container Types
Vials
liquid & lyo
Syringes
Ampoules
Cartridges
Pen delivery systems
Ready-to-Fill (RTF) Systems
Expertise in pre‑sterilized containers supplied in nest/tub configurations, eliminating the need for washing and depyrogenation steps. Capabilities include integration of Ready‑to‑Fill (RTF) systems with both existing and new filling lines, including adaptation of feed mechanisms and alignment with environmental monitoring requirements. Services also cover evaluation of RTF versus bulk container strategies, considering operational efficiency, contamination‑control needs, and overall cost‑effectiveness.
Vendor Relationships
Close working relationships with all leading filling line manufacturers worldwide:
